DOCUMENTED BY BATCHIdentity (HPLC)
High-performance liquid chromatography records the compound’s retention profile against a reference.
Research peptide
GHK-Cu
Lyophilized powder, catalogued by compound identity and backed by a certificate of analysis for its production batch.
For laboratory research only. Not for human or veterinary use.
Indicative · checkout opens at launch
Research use only
≥99% purity*
Batch tested
$60.00In stock
Size
Buying option
Buy now · $60.00100 in stock
Sealed, labelled vials · US delivery
| Quantity | 5–9 | 10+ |
|---|---|---|
| Discount | 10% | 15% |
| Price | $54.00 | $51.00 |
Indicative volume pricing, confirmed at launch.
View specifications Batch documentation Certificate of analysis
- Third-party tested
- Secure packaging
- Supplied for laboratory research
- Identity by HPLC & LC-MS Compound identity documented per batch.
- Batch-specific COA A certificate of analysis per batch.
- Secure packaging Sealed, labelled research vials.
- Third-party tested Independent testing per batch.
Documented by batch
Every batch is catalogued, tested and recorded.
Overview
GHK-Cu Research Peptide
Premium research-grade GHK-Cu for scientific and laboratory research.
GHK-Cu, also known as Copper Tripeptide-1 (the copper-binding tripeptide Gly-His-Lys), is a naturally occurring copper-binding tripeptide that has become one of the most extensively investigated compounds in tissue-remodelling biology, extracellular matrix research and connective tissue science. Originally identified in human plasma by Loren Pickart in the early 1970s, GHK-Cu has since been detected in several human tissues and biological fluids, including saliva and urine. Scientific investigations have shown that endogenous concentrations of GHK decline with age, prompting ongoing research into its physiological role and interactions with copper-dependent biological processes.
Unlike many synthetic research peptides developed specifically for pharmaceutical investigation, GHK-Cu is a naturally occurring signalling peptide that forms a stable complex with divalent copper ions (Cu²⁺). Copper is an essential trace element involved in numerous enzymatic reactions, connective tissue formation, antioxidant defence, mitochondrial respiration and cellular metabolism. Because GHK has a high affinity for copper, researchers have investigated its role as a copper transport peptide capable of delivering biologically available copper to cells and tissues under experimental conditions.
Why GHK-Cu is a focus of research
Over the past five decades, GHK-Cu has become one of the most widely studied copper peptides within molecular biology and tissue-remodelling research. Published investigations have explored several areas, including:
- extracellular matrix biology and collagen research
- elastin production and fibroblast activity
- angiogenesis and vascular biology
- antioxidant defence pathways
- cellular signalling pathways
- wound biology and tissue remodelling
Extracellular matrix research
One of the defining characteristics of GHK-Cu research is its interaction with extracellular matrix biology. Experimental studies have investigated the effects of GHK-Cu on fibroblast behaviour, collagen biology, elastin production, matrix polysaccharide metabolism and matrix metalloproteinase regulation. These processes are fundamental components of normal tissue maintenance and continue to represent major areas of laboratory investigation.
Fibroblast research
Fibroblasts are among the most extensively studied cell types in GHK-Cu research. Laboratory investigations have examined how GHK-Cu influences fibroblast migration, proliferation and extracellular matrix production under controlled experimental conditions.
Copper transport and homeostasis
Copper homeostasis represents another important area of scientific investigation. Researchers have proposed that GHK-Cu may function as a physiological copper transporter, facilitating the movement of copper ions to tissues requiring this essential trace element.
Collagen and connective tissue research
The relationship between GHK-Cu and collagen biology has generated particular scientific interest. Experimental investigations have examined collagen dynamics, extracellular matrix organisation and connective tissue remodelling following exposure to GHK-Cu in laboratory models.
Angiogenesis research
Angiogenesis, the formation of new blood vessels, represents another active area of GHK-Cu research. Investigators continue studying endothelial cell migration, vascular remodelling, capillary formation and angiogenic signalling pathways in controlled laboratory systems.
Gene expression research
Advances in molecular biology have also expanded interest in the influence of GHK-Cu on gene expression. Published experimental studies have reported modulation of numerous genes associated with extracellular matrix biology, cellular signalling, oxidative stress responses, cellular differentiation and tissue maintenance.
Dermatological and hair follicle research
The peptide has also become an important research tool in dermatological science and hair follicle biology, with laboratory studies investigating fibroblasts, keratinocytes, dermal papilla cells and extracellular matrix proteins.
Quality and documentation
At livvmore, GHK-Cu is supplied exclusively for laboratory research and scientific investigation. Every production batch undergoes quality control procedures designed to verify peptide identity, purity and consistency before release. Batch-specific Certificates of Analysis (COA) are available.
Researchers should recognise that although GHK-Cu has one of the strongest evidence bases among research peptides, many proposed molecular mechanisms continue to be investigated and should not be interpreted as established scientific conclusions.
For laboratory research use only. Not for human or veterinary use.
Documented by batchCatalogued by compound identity
Compound identityCAS · Molecular weight · Sequence
Batch recordsBatch · Lot · Production date
Independent testingHPLC · LC-MS
Specifications
Product specifications
Format
Lyophilized powder
Appearance
Powder
Molecular weight
~401 g/mol (copper(II) complex)
CAS number
89030-95-5
Sequence
Gly-His-Lys tripeptide, copper(II) complex
Storage
Store refrigerated at 2–8°C, protected from light and moisture. For extended storage, follow your laboratory's standard storage procedures.
Batch documentation
The certificate for the current batch
Every batch is third-party tested. The batch-specific certificate of analysis is available on request; the layout below shows the fields it records.
Certificate of analysis
Specimen layout
- Compound
- product identity
- Batch
- batch number
- Produced
- production date
- Appearance
- recorded appearance
- Identity (HPLC)
- recorded
- Mass (LC-MS)
- recorded
Specimen layout. A batch-specific certificate of analysis is issued for each production run and is available on request.
- Compound and batch identify the exact material supplied.
- Batch and production date tie the certificate to its production run.
- Identity records (HPLC, LC-MS) document what was tested on the batch.
Testing records
What each batch record documents
Every batch is accompanied by laboratory records. The entries below describe what each record documents.
Mass (LC-MS)
Mass spectrometry records the compound’s measured mass to document molecular identity.
Appearance
The physical appearance of the material is recorded, for example a white lyophilized powder.
Batch record
Each batch is logged with a lot number and production date for traceability.
These are records of laboratory testing carried out on the batch. They document compound identity for research use and are not a statement of safety, suitability, or fitness for any use.
Research information
GHK-Cu research information
GHK-Cu (Copper Tripeptide-1, the tripeptide Gly-His-Lys bound to copper(II)) is among the most extensively studied copper peptides in tissue-remodelling and extracellular-matrix research. Investigators have explored its biochemical properties, interactions with copper ions, extracellular matrix biology, collagen biology, wound biology, cellular signalling and gene regulation. The available evidence spans in vitro studies, animal research and a limited number of human investigations, with stronger evidence in skin biology than for many other proposed research applications.
Current areas of scientific investigation
- Collagen and extracellular matrix biology. Research has examined how GHK-Cu influences fibroblast activity, collagen biology, elastin production and matrix polysaccharide metabolism in experimental systems.
- Wound biology research. Experimental studies have investigated GHK-Cu in wound models, angiogenesis and tissue remodelling, examining cellular migration, matrix remodelling and growth-factor signalling.
- Gene expression. Microarray analyses have reported broad changes in gene-expression profiles associated with GHK-Cu exposure in experimental models.
- Skin biology. GHK-Cu has been widely investigated in dermatologic research involving fibroblasts, keratinocytes, dermal extracellular matrix biology and skin ageing.
- Hair follicle research. Laboratory investigations continue examining copper-peptide biology in hair follicle models, scalp physiology and dermal papilla cell biology.
- Angiogenesis and vascular biology. Researchers continue investigating endothelial-cell behaviour, angiogenesis, vascular remodelling and copper-dependent biological pathways.
- Molecular pharmacology. Current investigations examine copper binding, peptide stability, metalloproteinase regulation, antioxidant biology and peptide-mediated signalling pathways.
Current evidence landscape
GHK-Cu has one of the more substantial evidence bases among research peptides. Laboratory and animal studies consistently demonstrate biological activity across tissue-remodelling and extracellular-matrix pathways. Human evidence exists primarily in dermatologic and cosmetic research, but many studies are small and do not establish activity for broader research applications.
Scientific limitations
- Much of the mechanistic evidence derives from cell culture and animal studies.
- Human studies are generally small and often focus on cosmetic or dermatologic outcomes.
- Standardised pharmaceutical formulations remain under investigation.
- Additional pharmacokinetic and concentration-response studies are needed.
- Independent replication and larger controlled studies would strengthen the evidence base.
Selected scientific references
- Maquart FX, Pickart L, et al. FEBS Letters. 1988.
- Pickart L, Vasquez-Soltero JM, Margolina A. BioMed Research International. 2015.
- Pickart L, Margolina A. International Journal of Molecular Sciences. 2018.
- Pickart L. The Human Tripeptide GHK and Tissue Remodeling.
- Additional peer-reviewed publications examining wound biology, collagen biology and copper-peptide pharmacology.
The information presented summarises findings from the published scientific literature and is provided solely for scientific and educational purposes. livvmore supplies GHK-Cu exclusively for laboratory research use.
For laboratory research use only. Not for human or veterinary use.
Frequently asked questions
Questions and documentation
What is GHK-Cu?
GHK-Cu is catalogued in the Copper peptides collection and supplied as a lyophilized powder for in-vitro laboratory research. It is listed by CAS number 89030-95-5 and a molecular weight of ~401 g/mol (copper(II) complex). It is not for human or veterinary use.
What is the CAS number for GHK-Cu?
The CAS number recorded for GHK-Cu is 89030-95-5.
What is the molecular weight of GHK-Cu?
The molecular weight recorded for GHK-Cu is ~401 g/mol (copper(II) complex).
How is GHK-Cu supplied and stored?
GHK-Cu is supplied as a lyophilized powder. Store refrigerated at 2–8°C, protected from light and moisture. For extended storage, follow your laboratory's standard storage procedures.
What does research use only mean?
All products are supplied strictly for in-vitro laboratory research and are not for human or veterinary use, diagnosis, treatment, or personal consumption.
How are the products documented?
Every batch is third-party tested and documented. The certificate of analysis is available on request.
Is a certificate of analysis available?
Every batch is third-party tested, and the batch-specific certificate of analysis is available on request.
Who can purchase?
By placing an order, purchasers acknowledge that the product is intended solely for laboratory research use and agree to the Research Use Terms.
Fulfilment
How orders are handled
-
Secure packaging
Sealed, labelled research vials, packed to protect integrity in transit.
-
Third-party tested
Every batch is third-party tested; the certificate of analysis is available on request.
-
Research customers only
Supplied to qualified researchers for laboratory research use.
Shipping options and timelines are shown at checkout.
- Third-party tested Independent testing per batch
- Documented by batch Batch and lot records
- Certificate of analysis Available on request
- Identity by HPLC & LC-MS Compound identity documented
- Secure packaging Sealed, labelled research vials
- Supplied for laboratory research Research use only
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GHK-Cu
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