Tirzepatide (GLP2-TZ), catalogued at livvmore under the house code GLP2-TZ, is a synthetic 39-residue peptide supplied strictly as a laboratory research reference material. This profile sets out its verified chemical identity, structural features, physical characteristics, and the analytical methods used to confirm identity and purity per batch. Every figure below is drawn from public chemistry registries so that a receiving laboratory can reconcile the reference material against an independent record before any bench work begins.
Compound identity and CAS registry
Tirzepatide is registered under CAS number 2023788-19-2 and carries the development code LY3298176. In public chemistry registries it is indexed at PubChem under CID 166567236 (the compound name also resolves to several closely related PubChem records for the same molecule) and at DrugBank under accession DB15171. It is classified in the literature as a synthetic peptide and a dual GIP and GLP-1 receptor-agonist; this classification denotes the molecule’s mechanistic category in the literature and is not a statement of any outcome. livvmore supplies the compound only as a reference material for laboratory research, and the identifiers above let a laboratory tie the lot it receives to an independent registry entry.
Molecular formula, weight, and structure
The molecular formula recorded for tirzepatide is C225H348N48O68, corresponding to an average molecular weight of approximately 4813.5 g/mol (registry value 4813.527 g/mol). The molecule is a single linear chain of 39 amino acids terminating in a C-terminal amide. Its defining structural feature is a lipidation motif: a C20 fatty diacid (eicosanedioic acid) conjugated to the side chain of a lysine residue through a gamma-glutamic acid spacer and two AEEA (2-(2-aminoethoxy)ethoxy acetic acid) linker units. The stated molecular weight should be reconciled against the per-batch Certificate of Analysis rather than regarded as an exact figure for a given lot.
Amino-acid sequence and modifications
The 39-residue sequence, in single-letter notation with Aib marking the non-canonical residues, is Y-Aib-E-G-T-F-T-S-D-Y-S-I-Aib-L-D-K-I-A-Q-K-A-F-V-Q-W-L-I-A-G-G-P-S-S-G-A-P-P-P-S, carrying a C-terminal amide. Two of the positions, residue 2 and residue 13, are occupied by alpha-aminoisobutyric acid (Aib), a non-canonical residue not found among the standard twenty amino acids. The C20 fatty diacid conjugate is attached at the lysine at position 20 (Lys20) by way of the gamma-glutamic acid and dual AEEA linkers described above. The exact sequence and modifications of any given lot should be confirmed against its Certificate of Analysis.
Appearance, solubility, and storage
As a reference material, tirzepatide is supplied as a lyophilised white to off-white powder and is reported as soluble in aqueous buffers. The lyophilised powder is kept cold and desiccated, protected from light and from repeated freezing and thawing, and any aqueous solution is likewise held cold. As a lipidated peptide carrying a long-chain fatty diacid, it is stored and handled as a lipidated peptide reference standard. These notes describe storage and handling of the reference material at the bench only and are not use instructions.
Confirming identity and purity by LC-MS
Identity and purity are established by orthogonal analytical methods. Reversed-phase high-performance liquid chromatography (RP-HPLC) quantifies chromatographic purity as a percentage of total peak area, resolving the main peptide from process-related and degradation species. Liquid chromatography-mass spectrometry (LC-MS), including high-resolution mass spectrometry (HRMS), confirms identity by matching the measured mass against the theoretical mass calculated from the molecular formula. livvmore materials are identity- and purity-tested at the USC Alfred E. Mann Multi-Omics Mass Spectrometry Core, a university laboratory, by LC-MS/HRMS on a per-batch basis, with the resulting Certificate of Analysis published for each lot. The Certificate of Analysis is the authoritative record for the specific lot in hand, and all identity and purity figures should be read from it.
Related research peptides in the catalogue
Tirzepatide sits alongside the other GLP research reference materials catalogued at livvmore. Related entries include Retatrutide (GLP3-RT), Semaglutide (GLP1-SM), and Tirzepatide (GLP2-TZ), all within the GLP research peptide collection. For a side-by-side look at how these compounds differ in verified chemical identity, see the identity comparison.
For laboratory research use only. Not for human or veterinary use.
Frequently asked questions
What is the CAS number of Tirzepatide?
Tirzepatide is registered under CAS number 2023788-19-2 and carries the development code LY3298176. It is indexed at PubChem under CID 166567236 and at DrugBank under accession DB15171.
What is the molecular formula and molecular weight of Tirzepatide?
The molecular formula is C225H348N48O68, corresponding to an average molecular weight of approximately 4813.5 g/mol. The precise figure for a given lot should be reconciled against its Certificate of Analysis.
How many amino acids does Tirzepatide contain?
Tirzepatide is a single linear chain of 39 amino acids with a C-terminal amide. Positions 2 and 13 are occupied by the non-canonical residue alpha-aminoisobutyric acid (Aib), and a C20 fatty diacid is conjugated at the lysine at position 20 through a gamma-glutamic acid spacer and two AEEA linkers.
How is the identity and purity of Tirzepatide verified?
Identity is confirmed by LC-MS/HRMS, matching the measured mass against the theoretical mass from the molecular formula, and purity is measured by RP-HPLC as a percentage of total peak area. livvmore materials are tested at the USC Alfred E. Mann Multi-Omics Mass Spectrometry Core, a university laboratory, on a per-batch basis, with a Certificate of Analysis published for each lot.
How should lyophilised Tirzepatide reference material be stored at the bench?
The lyophilised powder is kept cold and desiccated, protected from light and from repeated freezing and thawing, and any aqueous solution is likewise held cold. These notes describe storage and handling of the reference material only and are not use instructions.